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Potassium Chloride, Sodium Chloride, Calcium Chloride, and Magnesium Chloride: Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx) Being discontinued since August 31, 2026
Strength:
119.3 mg/100 mL, 643 mg/100 mL, 17.6 mg/100 mL, 325.3 mg/100 mL

Patient information: uses, side effects, how to take - Potassium Chloride, Sodium Chloride, Calcium Chloride, and Magnesium Chloride

INSTRUCTIONS FOR USE

Flexible Plastic Container (free flex® bag)

Do not remove solution container from its overwrap until immediately before use.

The intact port cap provides visual tamper evidence. Do not use if port cap is prematurely removed. Maintain strict aseptic technique during handling.

To Open

  1. 1. Always inspect the solution container before and after removal from the overwrap.
  2. 2. Place the solution container on a clean, flat surface. Remove the solution container from the overwrap.
  3. 3. Check the solution container for leaks by squeezing firmly. If leaks are found, discard.

To add 10 mL of 8.4% Sodium Bicarbonate Injection, USP, and if other supplemental medication is desired, follow directions below before preparing for administration.

To Add Medication

  1. 1. Identify WHITE Additive Port with arrow pointing toward solution container.
  2. 2. Immediately before injecting additives, break off WHITE Additive Port Cap with the arrow pointing toward solution container.
  3. 3. Hold base of WHITE Additive Port.
  4. 4. Using aseptic technique, insert needle (18 to 23 gauge) through the center of WHITE Additive Port's septum and inject additives.
  5. 5. Mix solution container contents thoroughly.

Preparation for Administration

(Use aseptic technique)

  1. 1. Close the flow control clamp of the administration set.
  2. 2. Immediately before inserting the administration set, break off BLUE Infusion Port Cap with the arrow pointing away from solution container.
  3. 3. Hold the base of BLUE Infusion Port, twist and push the spike until the spike is fully inserted. NOTE: See full directions accompanying administration set.
  4. 4. The BLUE infusion port contains a self‐sealing septum that helps prevent leakage after removing the spike. The infusion port is not intended to be spiked more than once.
  5. 5. Suspend solution container from hanger hole.
  6. 6. Squeeze and release drip chamber to establish proper fluid level in chamber.
  7. 7. Attach aortic infusion device to set.
  8. 8. Open flow control clamp to expel air from set and aortic infusion device. Close clamp.
  9. 9. Position aortic infusion device to introduce solution into aortic root.
  10. 10. Regulate rate of administration with flow control clamp.
  11. 11. For Single use Only. Discard unused portion.

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 214623 · View the label on DailyMed

Revision date stated in the text: April 2022

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Potassium Chloride, Sodium Chloride, Calcium Chloride, and Magnesium Chloride

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Blood Coagulation Factor, Calculi Dissolution Agent, Osmotic Laxative, Phosphate Binder, Potassium Salt
Active ingredients Potassium chloride 119.3 mg/100 mL, Sodium chloride 643 mg/100 mL, Calcium chloride 17.6 mg/100 mL, Magnesium chloride 325.3 mg/100 mL
Dosage form Injection, solution
Route Intra-arterial
Marketing status listed in the FDA NDC Directory
Company (applicant) FRESENIUS KABI USA
FDA approval ANDA 214623Abbreviated New Drug Application (ANDA) – generic drug Approved February 18, 2022
Therapeutic equivalence (TE) code ATCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Generics Plegisol with the same TE code
Manufacturers 2 labelers list this drug on DailyMed
Drug shortage
  • Being discontinued since August 31, 2026
Packages (NDC)
Package
119.3 mg/100 mL, 643 mg/100 mL, 17.6 mg/100 mL, 325.3 mg/100 mL – 1000 ml in 1 bag / 1 in 1 pouch / 10 in 1 case NDC 65219-258-01

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.