Patient information: uses, side effects, how to take - Kalbitor
What is KALBITOR?
KALBITOR is a prescription medicine used to treat sudden attacks of hereditary angioedema (HAE) in people 12 years of age and older.
KALBITOR is not a cure for HAE.
It is not known if KALBITOR is safe and effective in children under 12 years of age.
Who should not receive KALBITOR?
Do not receive KALBITOR if you are allergic to KALBITOR.
What should I tell my doctor before I receive KALBITOR?
Before receiving KALBITOR, tell your doctor if you:
- have ever had an allergic reaction to KALBITOR. See "Who should not receive KALBITOR?"
are pregnant or plan to become pregnant. It is not known if KALBITOR will harm your unborn baby.
- are breast-feeding or plan to breast-feed. It is not known if KALBITOR passes into your breast milk.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list of them to show to your doctor and pharmacist when you get a new medicine.
How will I receive KALBITOR?
For each dose, you will receive 3 injections just under the skin (subcutaneous or SC injections) of your abdomen, thigh, or upper arm.
What are the possible side effects?
KALBITOR can cause serious allergic reactions. See "What is the most important information I should know about KALBITOR?"
Common side effects of KALBITOR include:
- headache
- nausea
- diarrhea
- fever
- injection site reactions, such as redness, rash, swelling, itching, or bruising
- stuffy nose
Call your doctor for advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
General information about KALBITOR
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. This Medication Guide gives you the most important information about KALBITOR. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about KALBITOR that is written for health professionals.
What are the ingredients of KALBITOR?
Active Ingredient: ecallantide
Inactive ingredients: disodium hydrogen orthophosphate (dihydrate), monopotassium phosphate, potassium chloride, sodium chloride in water for injection.
This Medication Guide has been approved by the U.S. Food and Drug Administration.
For more information, visit www.kalbitor.com or call 1-877-TAKEDA-7 (1-877-825-3327).
Manufactured by:
Takeda Pharmaceuticals U.S.A., Inc.
Cambridge, MA 02142
U.S. License No. 1898
KALBITOR and the KALBITOR Logo are registered trademarks of Dyax Corp.
Takeda and 
are registered trademarks of Takeda Pharmaceutical Company Limited.
© 2025 Takeda Pharmaceuticals U.S.A., Inc. All rights reserved.
Revised: 6/2025