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Hydrocortisone Rectal: Uses, Side Effects and Dosage

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Facts
Status:
Prescription (Rx)
Strength:
100 mg/60 mL
Brand names:
Drug class:
Active ingredient:
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Source: FDA drug labeling via NLM DailyMed · About this document

Patient information: uses, side effects, how to take - Hydrocortisone Rectal

How to use the retention enema:

Best results are achieved if the bowel is emptied immediately before the

enema is given.

1 Preparing the Medication for Administration

a Shake the bottle well to make sure that the suspension is homogeneous.

b Remove the protective sheath from the applicator tip. Hold the bottle at the neck so as not to cause any of the medication to be discharged.

2 Assuming the Correct Body Position

a Best results are obtained by lying on left side with the left leg extended and the right leg flexed forward for balance.

b An alternative to lying on the left side is the "knee-chest" position as shown here.

3 Administering the Retention Enema

a Gently insert the lubricated applicator tip into the rectum, pointed slightly toward the navel (umbilicus).

b Grasp the bottle firmly, then tilt slightly so that the nozzle is aimed toward the back, and squeeze slowly to instill the medication. Steady hand pressure will discharge most of the solution. After administering, withdraw and discard the used unit.

c Remain in position for at least 30 minutes to allow thorough distribution of the medication internally. Retain the enema all night, if possible.

Distributed by:

Avet Pharmaceuticals Inc.

East Brunswick, NJ 08816

1.866.901.DRUG (3784)

Revised: 1/2025

INS-926

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 075172 · View the label on DailyMed

Revision date stated in the text: January 2025

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Hydrocortisone Rectal

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Corticosteroid
Active ingredient Hydrocortisone 100 mg/60 mL
Dosage form Suspension
Route Rectal
Marketing status listed in the FDA NDC Directory
Company (applicant) CHARTWELL
FDA approval ANDA 075172Abbreviated New Drug Application (ANDA) – generic drug Approved December 3, 1999
Therapeutic equivalence (TE) code ABCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Manufacturers 3 labelers list this drug on DailyMed
Packages (NDC)
Package
100 mg/60 mL – 60 ml in 1 bottle / 1 in 1 carton NDC 23155-926-51
100 mg/60 mL – 60 ml in 1 bottle / 7 in 1 carton NDC 23155-926-81

Source: FDA drug labeling via NLM DailyMed, data as of November 7, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.