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Lidocaine and Prilocaine Topical: Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx)
Strength:
25 mg/g, 25 mg/g
Brand names:
Active ingredients:

Patient information: uses, side effects, how to take - Lidocaine and Prilocaine Topical

INSTRUCTIONS FOR USE SECTION

To measure 1 gram of lidocaine and prilocaine cream, the Cream should be gently squeezed out of the tube as a narrow strip that is 1.5 inches (3.8 cm) long and 0.2 inches (5 mm) wide. The strip of lidocaine and prilocaine cream should be contained within the lines of the diagram shown below.

Use the number of strips that equals your dose, like the examples in the table below.

Dosing Information

1 gram = 1 strip

2 grams = 2 strips

2.5 grams = 2.5 strips

For adult and pediatric patients, apply ONLY as prescribed by your physician.

If your child is below the age of 3 months or small for their age, please inform your doctor before applying lidocaine and prilocaine cream, which can be harmful, if applied over too much skin at one time in young children.

When applying lidocaine and prilocaine cream to the intact skin of young children, it is important that they be carefully observed by an adult in order to prevent the accidental ingestion of or eye contact with lidocaine and prilocaine cream.

lidocaine and prilocaine cream must be applied to intact skin at least 1 hour before the start of a routine procedure and for 2 hours before the start of a painful procedure. A protective covering of the cream is not necessary for absorption but may be helpful to keep the cream in place.

If using a protective covering, your doctor will remove it, wipe off the lidocaine and prilocaine cream, and clean the entire area with an antiseptic solution before the procedure. The duration of effective skin anesthesia will be at least 1 hour after removal of the protective covering.

Precautions

  1. 1. Do not apply near eyes or open wounds.
  2. 2. Keep out of the reach of children.
  3. 3. If your child becomes very dizzy, excessively sleepy, or develops duskiness of the face or lips after applying lidocaine and prilocaine cream, remove the cream and contact the child's physician at once.

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: NDA 019941 · View the label on DailyMed

Revision date stated in the text: June 2012

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Lidocaine and Prilocaine Topical

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Amide Local Anesthetic, Antiarrhythmic
Active ingredients Lidocaine 25 mg/g, Prilocaine 25 mg/g
Dosage form Cream
Route Topical
Marketing status not in the current FDA NDC Directory
Company (applicant) TEVA BRANDED PHARM
FDA approval NDA 019941New Drug Application (NDA) Approved December 30, 1992
Reference listed drug This is the reference listed drug (RLD) that generics are compared with.
Manufacturers 13 labelers list this drug on DailyMed
Packages (NDC)
Package
25 mg/g, 25 mg/g – 5 g in 1 tube NDC 61919-443-30

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.