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Ipratropium and Albuterol: Uses, Side Effects and Dosage

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Prescription (Rx)
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0.5 mg/3 mL, 2.5 mg/3 mL
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Source: FDA drug labeling via NLM DailyMed · About this document

Patient information: uses, side effects, how to take - Ipratropium and Albuterol

What is ipratropium bromide and albuterol sulfate inhalation solution?

Ipratropium bromide and albuterol sulfate inhalation solution is a combination of two medicines called bronchodilators. Ipratropium bromide and albuterol sulfate inhalation solution contains albuterol sulfate, which is a beta-adrenergic agonist, and ipratropium bromide, which is an anticholinergic. These two medicines work together to help open the airways in your lungs. Ipratropium bromide and albuterol sulfate inhalation solution is used to help treat airway narrowing (bronchospasm) that happens with chronic obstructive pulmonary disease (COPD) in adult patients who need to use more than one bronchodilator medicine.

Who should not use ipratropium bromide and albuterol sulfate inhalation solution?

Do not use ipratropium bromide and albuterol sulfate inhalation solution if you: Are allergic to any of the ingredients in ipratropium bromide and albuterol sulfate inhalation solution or to atropine. The active ingredients are albuterol sulfate and ipratropium bromide. See the end of this leaflet for a complete list of ingredients in ipratropium bromide and albuterol sulfate inhalation solution.

Ipratropium bromide and albuterol sulfate inhalation solution has not been studied in patients younger than 18 years of age.

What should I tell my doctor before I start using ipratropium bromide and albuterol sulfate inhalation solution?

Tell your doctor about all of your conditions, including if you:

  • Have heart problems. This includes coronary artery disease and heart rhythm problems.
  • Have high blood pressure
  • Have diabetes
  • Have or had seizures
  • Have a thyroid problem called hyperthyroidism
  • Have an eye problem called narrow-angle glaucoma
  • Have liver or kidney problems
  • Have problems urinating due to bladder-neck blockage or an enlarged prostate (men)
  • Are pregnant or planning to become pregnant. It is not known if ipratropium bromide and albuterol sulfate inhalation solution can harm your unborn baby. You and your doctor will have to decide if ipratropium bromide and albuterol sulfate inhalation solution is right for you during a pregnancy.
  • Are breastfeeding. It is not known if ipratropium bromide and albuterol sulfate inhalation solution passes into your milk or if it can harm your baby. You and your doctor should decide whether you should take ipratropium bromide and albuterol sulfate inhalation solution or breastfeed, but not both.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins and herbal supplements. Ipratropium bromide and albuterol sulfate inhalation solution and other medicines can interact. This may cause serious side effects. Especially tell your doctor if you take:

  • Other medicines that contain anticholinergics such as ipratropium bromide. This also includes medicines used for Parkinson's disease.
  • Other medicines that contain beta-agonists such as albuterol sulfate. These are usually used to treat airway narrowing (bronchospasm).
  • Medicines called beta-blockers. These are usually used for high blood pressure or heart problems.
  • Medicines called "water pills" (diuretics)
  • Medicines for depression called monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants.

Ask your doctor or pharmacist if you are not sure if you take any of these types of medicines. Know the medicines you take. Keep a list of them and show it to your doctor and pharmacists when you get a new medicine.

How should I use ipratropium bromide and albuterol sulfate inhalation solution?

  • Read the Patient's Instructions for Use that you get with your prescription. Talk to your doctor or pharmacist if you have any questions.
  • Take ipratropium bromide and albuterol sulfate inhalation solution exactly as prescribed by your doctor. Do not change your dose or how often you use ipratropium bromide and albuterol sulfate inhalation solution without talking to your doctor. Inhale ipratropium bromide and albuterol sulfate inhalation solution through your mouth and into your lungs using a machine called a nebulizer.
  • Ipratropium bromide and albuterol sulfate inhalation solution may help to open your airways for up to 5 hours after taking this medicine. If ipratropium bromide and albuterol sulfate inhalation solution does not help your airway narrowing (bronchospasm) or your bronchospasm gets worse, call your doctor right away or get emergency help if needed.

What should I avoid while using ipratropium bromide and albuterol sulfate inhalation solution?

Do not get ipratropium bromide and albuterol sulfate inhalation solution in your eyes. Be careful not to spray ipratropium bromide and albuterol sulfate inhalation solution in your eyes while you are using your nebulizer. Ipratropium bromide and albuterol sulfate inhalation solution can cause the following short-term eye problems:

  • Enlarged pupils
  • Blurry vision
  • Eye pain

Ipratropium bromide and albuterol sulfate inhalation solution can cause a serious eye problem called narrow-angle glaucoma or worsen the narrow-angle glaucoma you already have.

What are the possible side effects with ipratropium bromide and albuterol sulfate inhalation solution?

Ipratropium bromide and albuterol sulfate inhalation solution may cause the following serious side effects:

  • Worsening of the narrowing in your airways (bronchospasm). This side effect can be life-threatening and has happened with both of the medicines that are in ipratropium bromide and albuterol sulfate inhalation solution. Stop ipratropium bromide and albuterol sulfate inhalation solution and call your doctor right away or get emergency help if your breathing problems get worse while or after using ipratropium bromide and albuterol sulfate inhalation solution.

  • Serious and life-threatening allergic reactions. Symptoms of a serious allergic reaction include:

    • Hives, rash
    • Swelling of your face, eyelids, lips, tongue, or throat, and trouble swallowing
    • Worsening of your breathing problems such as wheezing, chest tightness or shortness of breath
    • Shock (loss of blood pressure and consciousness)

The most common side effects with ipratropium bromide and albuterol sulfate inhalation solution include lung disease, sore throat, chest pain, constipation, diarrhea, bronchitis, urinary tract infection, leg cramps, nausea, upset stomach, voice changes, and pain.

These are not all the side effects with ipratropium bromide and albuterol sulfate inhalation solution. For a complete list, ask your doctor or pharmacist.

How should I store ipratropium bromide and albuterol sulfate inhalation solution?

  • Store ipratropium bromide and albuterol sulfate inhalation solution at 20° to 25°C (68° to 77°F); excursions permitted between 15° and 30°C (59° and 86°F). Protect from light. Unit dose vials should remain stored in the protective foil pouch at all times. Once removed from the foil pouch, the individual vials should be used within one week. Discard if solution is not colorless.
  • Safely discard ipratropium bromide and albuterol sulfate inhalation solution that is out-of-date or no longer needed.
  • Keep ipratropium bromide and albuterol sulfate inhalation solution and all medicines out of the reach of children.

General advice about Ipratropium Bromide and Albuterol Sulfate Inhalation Solution

Medicines are sometimes prescribed for conditions that are not mentioned in the patient information leaflets. Do not use ipratropium bromide and albuterol sulfate inhalation solution for a condition for which it was not prescribed. Do not give ipratropium bromide and albuterol sulfate inhalation solution to other people, even if they have the same symptoms you have. It may harm them.

This leaflet summarizes the most important information about ipratropium bromide and albuterol sulfate inhalation solution. If you would like more information, talk with your doctor. You can ask your doctor or pharmacist for information about ipratropium bromide and albuterol sulfate inhalation solution that is written for healthcare professionals.

What are the ingredients in ipratropium bromide and albuterol sulfate inhalation solution ?

Active Ingredients: ipratropium bromide, USP and albuterol sulfate, USP

Inactive Ingredients: sodium chloride, hydrochloric acid, edetate sodium, USP and water for injection.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Distributed by:

Sun Pharmaceutical Industries, Inc.

Cranbury, NJ 08512

Manufactured by:

Sun Pharmaceutical Industries Limited

Baska Ujeti Road, Ujeti

Halol-389350, Gujarat, India

5269258

Rev. 01/2026

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 207875 · View the label on DailyMed

Revision date stated in the text: January 2026

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Ipratropium and Albuterol

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Anticholinergic, beta2-Adrenergic Agonist
Active ingredients Ipratropium bromide 0.5 mg/3 mL, Albuterol sulfate 2.5 mg/3 mL
Dosage form Solution
Route Respiratory (inhalation)
Marketing status listed in the FDA NDC Directory
Company (applicant) SUN PHARM
FDA approval ANDA 207875Abbreviated New Drug Application (ANDA) – generic drug Approved August 7, 2017
Therapeutic equivalence (TE) code ANCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Manufacturers 11 labelers list this drug on DailyMed
Packages (NDC)
Package
0.5 mg/3 mL, 2.5 mg/3 mL – 3 ml in 1 vial / 5 in 1 pouch / 6 in 1 carton NDC 47335-756-49
0.5 mg/3 mL, 2.5 mg/3 mL – 3 ml in 1 vial / 5 in 1 pouch / 12 in 1 carton NDC 47335-756-52

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.