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Timolol Ophthalmic (Timoptic): Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx)
Strength:
2.5 mg/mL, 5 mg/mL
Brand names:
Active ingredient:

Patient information: uses, side effects, how to take - Timolol Ophthalmic

Instructions for Use

Timolol (tye-MOE-lawl) Maleate

ophthalmic solution 0.25% and 0.5%

Read this Instructions for Use that comes with timolol maleate ophthalmic solution before you start using it and each time you get a refill. There may be new information. This information does not take the place of talking with your doctor about your medical condition or treatment.

Important information about timolol maleate ophthalmic solution:

  • Use timolol maleate ophthalmic solution exactly as your doctor tells you to use it. Your doctor will tell you how much timolol maleate ophthalmic solution to use and when to use it.
  • If you use other medicines in your eye, wait at least 10 minutes between using timolol maleate ophthalmic solution and your other eye medicines.
  • Do not touch your eye or areas around your eye with the tip of the timolol maleate ophthalmic solution bottle.You may get bacteria on the tip of the bottle that can cause you to get an eye infection that can lead to serious eye damage or vision loss.

How should I use timolol maleate ophthalmic solution?

Step 1. Wash your hands.

Step 2. Turn your closed bottle of timolol maleate ophthalmic solution upside down (invert) and shake once.

Step 3. Remove the timolol maleate ophthalmic solution cap by turning the cap in the direction of the arrows shown (See Figure A). Put the cap in a clean and dry area. Do not let the tip of the bottle touch your fingers or other surfaces.

Figure A

Step 4. Hold the bottle between your thumb and index finger with 1 hand. Use the index finger of the other hand to pull down the lower eyelid to form a pocket for the eye drop (See Figure B). Tilt your head backwards.

Figure B

Step 5. Place the tip of the bottle close to your eye. Be careful not to touch your eye with the tip of the bottle. Gently squeeze the bottle and let 1 drop fall into the space between your lower eyelid and your eye (See Figure C). If a drop misses your eye, follow the instructions in steps 4 and 5 again.

Figure C

Step 6. If your doctor has told you to use timolol maleate ophthalmic solution in both eyes, repeat steps 4 and 5 for your other eye.

Step 7. Put the cap back on the bottle and close.

  • The timolol maleate ophthalmic solution bottle tip is made to give 1 drop at a time. Do not try to make the hole in the tip of your bottle bigger.
  • Do not wash the bottle tip.
  • After you have used all of your timolol maleate ophthalmic solution doses, there will be some timolol maleate ophthalmic solution left in the bottle. Do not try to remove the extra timolol maleate ophthalmic solution from the bottle. Throw it away.

How should I store timolol maleate ophthalmic solution?

  • Store timolol maleate ophthalmic solution at room temperature between 59°F to 77°F (15°C to 25°C) in an upright position.
  • Do not freeze timolol maleate ophthalmic solution.
  • Keep timolol maleate ophthalmic solution out of light.

Keep timolol maleate ophthalmic solution and all medicines out of the reach of children.

If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for more information about timolol maleate ophthalmic solution that is written for health professionals.

This Instructions for Use has been approved by the U.S. Food and Drug Administration.

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 217764 · View the label on DailyMed

Revision date stated in the text: May 2024

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Timolol Ophthalmic

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class beta-Adrenergic Blocker
Active ingredient Timolol maleate
Dosage form Solution/ drops
Route Ophthalmic
Marketing status listed in the FDA NDC Directory
Company (applicant) SOMERSET
FDA approval ANDA 217764Abbreviated New Drug Application (ANDA) – generic drug Approved July 3, 2024
Therapeutic equivalence (TE) code AT1Codes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Generics Betimol, Istalol with the same TE code
Manufacturers 24 labelers list this drug on DailyMed
Recalls
  • July 5, 2025: Class II recall: Defective Container: spike of the cap becomes lodged in the nozzle of the product bottle.
  • April 18, 2025: Class II recall: Defective Container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle.
  • January 23, 2025: Class II recall: Defective Container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle.
Show more recalls (2)+
  • December 5, 2024: Class II recall: Defective Container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle.
  • October 29, 2024: Class II recall: Defective Container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle
Packages (NDC)
Package
2.5 mg/mL – 5 ml in 1 bottle / 1 in 1 carton NDC 70069-701-01
2.5 mg/mL – 10 ml in 1 bottle / 1 in 1 carton NDC 70069-702-01
2.5 mg/mL – 15 ml in 1 bottle / 1 in 1 carton NDC 70069-703-01
5 mg/mL – 5 ml in 1 bottle / 1 in 1 carton NDC 70069-706-01
5 mg/mL – 10 ml in 1 bottle / 1 in 1 carton NDC 70069-707-01
5 mg/mL – 15 ml in 1 bottle / 1 in 1 carton NDC 70069-708-01

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.