Medication-info.com Search Menu

Selexipag: Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx)
Strength:
200 mcg, 400 mcg, 600 mcg, 800 mcg, 1000 mcg, 1200 mcg, 1400 mcg, 1600 mcg
Drug class:
Active ingredient:

Source: FDA drug labeling via NLM DailyMed · About this document

Patient information: uses, side effects, how to take - Selexipag

What is selexipag tablets?

  • Selexipag tablets are a prescription medicine used to treat adults with pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs.
  • Selexipag tablets can help slow down the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if selexipag tablets are safe and effective in children younger than 2 years of age.

Do not take selexipag tablets if you:

  • are allergic to selexipag or any of the other ingredients in selexipag tablets (see the end of the Patient Information leaflet for a complete list of ingredients)
  • take gemfibrozil because this medicine may affect how selexipag tablets works and cause side effects.

Before you take selexipag tablets, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems.
  • have narrowing of the pulmonary veins, a condition called pulmonary veno-occlusive disease.

  • are pregnant or plan to become pregnant. It is not known if selexipag tablets will harm your unborn baby.

  • are breastfeeding or plan to breastfeed. It is not known if selexipag passes into your breast milk. You and your healthcare provider should decide if you will take selexipag tablets or breastfeed. You should not do both.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Selexipag tablets and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider.

How should I take selexipag tablets?

  • Take selexipag tablets exactly as your healthcare provider tells you to take it. Do not stop taking selexipag tablets unless your healthcare provider tells you to stop.
  • Your healthcare provider will slowly increase your dose to find the dose of selexipag tablets that is right for you.
  • If you have side effects, your healthcare provider may tell you to change your dose of selexipag tablets.

  • Selexipag tablets can be taken with or without food. Taking selexipag tablets with food may help you tolerate selexipag tablets better.

  • Selexipag tablets are usually taken 2 times each day.
  • Swallow selexipag tablets whole. Do not split or crush selexipag tablets.
  • If you miss a dose of selexipag tablets, take it as soon as you remember. If your next scheduled dose is due within 6 hours, skip the missed dose. Take the next dose at your regular time.
  • If you miss 3 or more days of selexipag tablets, call your healthcare provider to see if your dose needs to be changed.
  • If you take too much selexipag tablets, call your healthcare provider or go to the nearest hospital emergency room right away.

What are the possible side effects of selexipag tablets?

The most common side effects of selexipag tablets include:

  • headache
  • diarrhea
  • pain in joints
  • rash
  • jaw pain
  • nausea
  • low red blood cell count
  • decreased appetite
  • muscle pain
  • vomiting
  • pain in arms or legs
  • flushing

These are not all of the possible side effects of selexipag tablets.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store selexipag tablets?

  • Store selexipag tablets at room temperature between 68°F and 77°F (20°C and 25°C).

Keep selexipag tablets and all medicines out of the reach of children.

General information about the safe and effective use of selexipag tablets

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet.

Do not use selexipag tablets for a condition for which it was not prescribed. Do not give selexipag tablets to other people, even if they have the same symptoms that you have. It may harm them. You can ask your healthcare provider or pharmacist for information about selexipag tablets that is written for health professionals.

What are the ingredients in selexipag tablets?

Active ingredient: selexipag

Inactive ingredients: corn starch, colloidal silicon dioxide, hydroxypropyl cellulose, low substituted hydroxypropyl cellulose, microcrystalline cellulose and magnesium stearate. The tablets are film coated with a coating material containing hypromellose, propylene glycol, carnauba wax, titanium dioxide, along with mixtures of ferrosoferric oxide, iron oxide red or iron oxide yellow.

Pediatric use information is approved for Actelion Pharmaceuticals US, Inc.'s Uptravi® (Selexipag) Tablets. However, due to Actelion Pharmaceuticals US, Inc.'s marketing exclusivity rights, this drug product is not labeled with that information.

The trademarks referenced are owned by third parties not affiliated with Zydus Pharmaceuticals (USA) Inc.

Manufactured by:

Zydus Lifesciences Ltd.

Ahmedabad, India

For more information, call 1-877-993-8779.

The Patient Information has been approved by the U.S. Food and Drug Administration.

Revised: 10/2026

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 214302 · View the label on DailyMed

Revision date stated in the text: October 2026

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Selexipag

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Prostacyclin Receptor Agonist
Active ingredient Selexipag
Dosage form Tablet, film coated, Kit
Route Oral
Marketing status not in the current FDA NDC Directory
Company (applicant) ZYDUS LIFESCIENCES
FDA approval ANDA 214302Abbreviated New Drug Application (ANDA) – generic drug Approved December 21, 2022
Manufacturers 2 labelers list this drug on DailyMed
Packages (NDC)
Package
200 mcg – 60 in 1 bottle NDC 70771-1793-6
200 mcg – 140 in 1 bottle NDC 70771-1793-8
400 mcg – 60 in 1 bottle NDC 70771-1794-6
600 mcg – 60 in 1 bottle NDC 70771-1795-6
800 mcg – 60 in 1 bottle NDC 70771-1796-6
1000 mcg – 60 in 1 bottle NDC 70771-1797-6
1200 mcg – 60 in 1 bottle NDC 70771-1798-6
1400 mcg – 60 in 1 bottle NDC 70771-1799-6
1600 mcg – 60 in 1 bottle NDC 70771-1800-6
200 mcg, 800 mcg – 1 in 1 carton NDC 70771-1801-7

Source: FDA drug labeling via NLM DailyMed, data as of November 5, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.