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Prevacid (Lansoprazole): Uses, Side Effects and Dosage

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Prescription (Rx)
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30 mg, 15 mg
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Source: FDA drug labeling via NLM DailyMed · About this document

Patient information: uses, side effects, how to take - Prevacid

What are PREVACID and PREVACID SoluTab?

A prescription medicine called a proton pump inhibitor (PPI) used to reduce the amount of acid in your stomach.

In adults, PREVACID and PREVACID SoluTab are used for:

  • 4 weeks for the healing and symptom relief of duodenal ulcers.
  • 10 to 14 days with certain antibiotics to treat an infection caused by bacteria called H. pylori.
  • maintaining healing of duodenal ulcers. PREVACID has not been studied beyond 12 months for this purpose.
  • up to 8 weeks for the healing and symptom relief of stomach ulcers.
  • up to 8 weeks for the healing of stomach ulcers in people taking pain medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). PREVACID has not been studied beyond 8 weeks for this purpose.
  • reducing the risk of stomach ulcers in people who are at risk of developing stomach ulcers with NSAIDs. PREVACID has not been studied beyond 12 weeks for this purpose.

  • up to 8 weeks to treat heartburn and other symptoms that happen with gastroesophageal reflux disease (GERD).

    GERD happens when acid in your stomach backs up into the tube (esophagus) that connects your mouth to your stomach. This may cause a burning feeling in your chest or throat, sour taste or burping.

  • up to 8 weeks for the healing and symptom relief of acid-related damage to the lining of the esophagus (called erosive esophagitis or EE). Your doctor may prescribe another 8 to 16 weeks of PREVACID or PREVACID SoluTab for patients whose EE does not improve or whose symptoms return.
  • maintaining healing of EE. PREVACID has not been studied beyond 12 months for this purpose.
  • the long-term treatment of conditions where your stomach makes too much acid. This includes a rare condition called Zollinger-Ellison syndrome.

Children:

Give PREVACID and PREVACID SoluTab exactly as prescribed by your child's doctor. Do not increase the dose of PREVACID and PREVACID SoluTab or give your child PREVACID and PREVACID SoluTab longer than the amount of time your doctor tells you to.

In children 1 to 11 years of age, PREVACID and PREVACID SoluTab are used for:

  • up to 12 weeks to treat heartburn and other symptoms that can happen with GERD.
  • up to 12 weeks for the healing and symptom relief of EE.

In children 12 to 17 years of age, PREVACID and PREVACID SoluTab are used for:

  • up to 8 weeks to treat heartburn and other symptoms that can happen with GERD.
  • up to 8 weeks for the healing and symptom relief of EE.

PREVACID and PREVACID SoluTab are not recommended for treating the symptoms of GERD in children less than 1 year of age and may harm them.

Do not take PREVACID or PREVACID SoluTab if you are:

  • allergic to lansoprazole, any other PPI medicine, or any of the ingredients in PREVACID or PREVACID SoluTab. See the end of this Medication Guide for a complete list of ingredients in PREVACID and PREVACID SoluTab.
  • taking a medicine that contains rilpivirine (EDURANT, COMPLERA, ODEFSEY, JULUCA) used to treat HIV-1 (Human Immunodeficiency Virus).

Before you take PREVACID or PREVACID SoluTab, tell your doctor about all of your medical conditions, including if you:

  • have low magnesium, calcium, potassium or sodium levels in your blood or you are taking a diuretic.
  • have liver problems.
  • have phenylketonuria. PREVACID SoluTab contains aspartame.
  • are pregnant, think you may be pregnant or plan to become pregnant. PREVACID or PREVACID SoluTab may harm your unborn baby. Talk to your doctor about the possible risks to an unborn baby if PREVACID or PREVACID SoluTab is taken during pregnancy.

  • are breastfeeding or plan to breastfeed. It is not known if PREVACID or PREVACID SoluTab passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take PREVACID or PREVACID SoluTab.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take methotrexate (OTREXUP, RASUVO, TREXALL, REDITREX, XATMEP).

How should I take PREVACID and PREVACID SoluTab?

  • Take PREVACID or PREVACID SoluTab exactly as prescribed by your doctor.
  • Do not change your dose or stop taking PREVACID or PREVACID SoluTab without talking to your doctor.

  • Take PREVACID or PREVACID SoluTab before meals.

    PREVACID capsules:

    • Swallow PREVACID capsules whole.
    • Do not crush or chew PREVACID capsules.
    • If you have trouble swallowing a whole capsule, you can open the capsule and take the contents with certain foods or juices. See the "Instructions for Use" at the end of this Medication Guide for instructions on how to take PREVACID capsules with certain foods or juices.
    • See the "Instructions for Use" at the end of this Medication Guide for instructions on how to mix and give PREVACID capsules through a nasogastric tube (NG tube).

    PREVACID SoluTab:

    • PREVACID SoluTab is a tablet that melts in your mouth with or without water.
    • Do not break, cut, crush or chew the tablets.
    • See the "Instructions for Use" at the end of this Medication Guide for instructions on how to mix and give PREVACID SoluTab through a syringe and NG tube.
  • If you miss a dose of PREVACID or PREVACID SoluTab, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take your next dose at your regular time. Do not take 2 doses at the same time.
  • If you take too much PREVACID or PREVACID SoluTab, call your doctor or your poison control center at 1-800-222-1222 right away or go to the nearest hospital emergency room.

What are the possible side effects of PREVACID and PREVACID SoluTab?

PREVACID and PREVACID SoluTab can cause serious side effects, including:

  • See "What is the most important information that I should know about PREVACID and PREVACID SoluTab?".
  • Low vitamin B12 levels in the body can happen in people who have taken PREVACID or PREVACID SoluTab for a long time (more than 3 years). Tell your doctor if you have symptoms of low vitamin B12 levels, including shortness of breath, lightheadedness, irregular heartbeat, muscle weakness, pale skin, feeling tired, mood changes, and tingling or numbness in the arms and legs.
  • Stomach growths (fundic gland polyps). People who take PPI medicines for a long time have an increased risk of developing a certain type of stomach growth called fundic gland polyps, especially after taking PPI medicines for more than 1 year.
  • Low magnesium levels in the body can happen in people who have taken PREVACID for at least 3 months. Tell your doctor right away if you have symptoms of low magnesium levels, including seizures, dizziness, irregular heartbeat, jitteriness, muscle aches or weakness, and spasms of hands, feet or voice.

  • Severe skin reactions. PREVACID can cause rare but severe skin reactions that may affect any part of your body. These serious skin reactions may need to be treated in a hospital and may be life threatening:

    • Skin rash which may have blistering, peeling or bleeding on any part of your skin (including your lips, eyes, mouth, nose, genitals, hands or feet).
    • You may also have fever, chills, body aches, shortness of breath, or enlarged lymph nodes.

    Stop taking PREVACID and call your doctor right away. These symptoms may be the first sign of a severe skin reaction.

The most common side effects of PREVACID and PREVACID SoluTab include: diarrhea, stomach-area (abdomen) pain, nausea and constipation.

These are not all the possible side effects of PREVACID and PREVACID SoluTab.

Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088.

How should I store PREVACID and PREVACID SoluTab?

Store PREVACID at room temperature between 68°F to 77°F (20°C to 25°C).

Keep PREVACID and PREVACID SoluTab and all medicines out of the reach of children.

General information about the safe and effective use of PREVACID and PREVACID SoluTab.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use PREVACID or PREVACID SoluTab for conditions for which it was not prescribed. Do not give PREVACID or PREVACID SoluTab to other people, even if they have the same symptoms that you have. It may harm them. You can ask your doctor or pharmacist for information about PREVACID and PREVACID SoluTab that is written for health professionals.

What are the ingredients in PREVACID and PREVACID SoluTab?

Active ingredient: lansoprazole.

Inactive ingredients in PREVACID capsules: sugar sphere, sucrose, methacrylic acid copolymer, low substituted hydroxypropyl cellulose, starch, magnesium carbonate, talc, polyethylene glycol, titanium dioxide, polysorbate 80, hydroxypropyl cellulose, colloidal silicon dioxide, D&C Red No. 28, FD&C Blue No. 1, and FD&C Red No. 40.

Inactive ingredients in PREVACID SoluTab: mannitol, methacrylic acid, hydroxypropyl cellulose, lactose monohydrate-microcrystalline cellulose sphere, triethyl citrate, crospovidone, polyacrylate, magnesium carbonate, aspartame, glyceryl monostearate, hypromellose, magnesium stearate, citric acid, titanium dioxide, talc, artificial strawberry flavor, polyethylene glycol, polysorbate 80 and ferric oxide.

PREVACID SoluTab contains 2.5 mg of phenylalanine in each 15 mg tablet and 5.1 mg of phenylalanine in each 30 mg tablet.

Distributed by: Takeda Pharmaceuticals America, Inc., Cambridge, MA 02142

PREVACID is a trademark registered in the U.S. Patent and Trademark Office and SoluTab is a trademark of Takeda Pharmaceuticals U.S.A., Inc. and used under license by Takeda Pharmaceuticals America, Inc.

All other trademark names are the property of their respective owners.

©2025 Takeda Pharmaceuticals America, Inc. All rights reserved.

For more information go to www.PREVACID.com or call 1-877- TAKEDA-7 (1-877- 825-3327).

INSTRUCTIONS FOR USE

PREVACID (prev-a-sid)

(lansoprazole) delayed-release capsules, for oral use

and

PREVACID SoluTab (prev-a-sid sol-u-tab)

(lansoprazole) delayed-release orally disintegrating tablets

Important:

  • Take PREVACID or PREVACID SoluTab before meals.
  • Do not crush or chew PREVACID capsules or PREVACID SoluTab.
  • PREVACID or PREVACID SoluTab should only be used with the foods and juices listed below.

PREVACID delayed-release capsules (PREVACID capsules)

Taking PREVACID capsules with certain foods:

You can only use applesauce, ENSURE pudding, cottage cheese, yogurt or strained pears.

  1. 1. Open the capsule.
  2. 2. Sprinkle the granules on 1 tablespoon of applesauce, ENSURE pudding, cottage cheese, yogurt or strained pears.
  3. 3. Swallow right away.

Taking PREVACID capsules with certain juices:

You can only use apple juice, orange juice or tomato juice.

  1. 1. Open the capsule.
  2. 2. Sprinkle the granules into 60 mL (about ¼ cup) of apple juice, orange juice or tomato juice.
  3. 3. Stir.
  4. 4. Swallow right away.
  5. 5. To make sure that the entire dose is taken, add 1/2 cup or more of juice to the glass, stir and swallow right away.

Giving PREVACID capsules through a nasogastric tube (NG tube) size 16 French or larger:

You can only use apple juice.

  1. 1. Place 40 mL of apple juice into a clean container.
  2. 2. Open the capsule and empty the granules into the container of apple juice.
  3. 3. Use a catheter-tip syringe to draw up the apple juice and granule mixture.
  4. 4. Gently mix the catheter-tip syringe to keep the granules from settling.
  5. 5. Attach the catheter-tip syringe to the NG tube.
  6. 6. Give the mixture right away through the NG tube that goes into the stomach. Do not save the apple juice and granule mixture for later use.
  7. 7. Refill the catheter-tip syringe with 40 mL of apple juice and mix gently. Flush the NG tube with apple juice.

PREVACID SoluTab Delayed-Release Orally Disintegrating Tablets (PREVACID SoluTab)

  1. 1. Do not chew, crush, cut or break the tablets.
  2. 2. Put the tablet on the tongue and let it dissolve, with or without water.
  3. 3. Swallow after the tablet dissolves.
  4. 4. The tablet usually dissolves in less than 1 minute.

For patients who have trouble swallowing tablets, PREVACID SoluTab can be given as follows:

Giving PREVACID SoluTab with water using an oral syringe:

  1. 1. Put a 15 mg tablet in an oral syringe and draw up 4 mL of water into the oral syringe, or put a 30 mg tablet in an oral syringe and draw up 10 mL of water into the oral syringe.
  2. 2. Gently shake the oral syringe to mix the tablet and the water.
  3. 3. After the tablet is mixed in the water, place the tip of the oral syringe in the mouth. Give the medicine within 15 minutes of mixing. Do not save the tablet and water mixture for later use.
  4. 4. Refill the oral syringe with about 2 mL of water for the 15 mg tablet or 5 mL of water for the 30 mg tablet, and shake gently. Place the tip of the oral syringe in the mouth and give the medicine that is left in the syringe.

Giving PREVACID SoluTab with water through a nasogastric tube (NG tube) size 8 French or larger:

  1. 1. Put a 15 mg tablet in a catheter-tip syringe and draw up 4 mL of water, or put a 30 mg tablet in a catheter-tip syringe and draw up 10 mL of water.
  2. 2. Gently shake the catheter-tip syringe to mix the tablet and the water.
  3. 3. Connect the catheter-tip syringe to the NG tube.
  4. 4. Give the mixture right away through the NG tube that goes into the stomach. Give the medicine within 15 minutes of mixing. Do not save the granule and water mixture for later use.
  5. 5. Refill the catheter-tip syringe with about 5 mL of water and shake gently. Flush the NG tube with the water.

How should I store PREVACID and PREVACID SoluTab?

  • Store PREVACID capsules and PREVACID SoluTab at room temperature between 68°F to 77°F (20°C to 25°C).

Keep PREVACID and PREVACID SoluTab and all medicines out of the reach of children.

This Instruction for Use has been approved by the U.S. Food and Drug Administration.

Distributed by:

Takeda Pharmaceuticals America, Inc.

Cambridge, MA 02142

Revised: March 2025

PREVACID is a trademark registered in the U.S. Patent and Trademark Office and SoluTab is a trademark of Takeda Pharmaceuticals U.S.A., Inc. and used under license by Takeda Pharmaceuticals America, Inc.

All other trademark names are the property of their respective owners.

©2025 Takeda Pharmaceuticals America, Inc. All rights reserved.

PRV012 R57

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: NDA 020406 · View the label on DailyMed

Revision date stated in the text: March 2025

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Prevacid

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Proton Pump Inhibitor
Active ingredient Lansoprazole
Dosage form Capsule, delayed release, Tablet, orally disintegrating, delayed release
Route Oral
Marketing status listed in the FDA NDC Directory
Company (applicant) TAKEDA PHARMS USA
FDA approval NDA 020406New Drug Application (NDA) Approved May 10, 1995
Reference listed drug This is the reference listed drug (RLD) that generics are compared with.
Therapeutic equivalence (TE) code ABCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Manufacturers 1 labelers list this drug on DailyMed
Packages (NDC)
Package
30 mg – 100 in 1 bottle NDC 64764-046-13
30 mg – 1000 in 1 bottle NDC 64764-046-19
30 mg – 10 in 1 blister pack / 10 in 1 carton NDC 64764-046-11
30 mg – 4 in 1 blister pack / 5 in 1 tray NDC 64764-046-06
15 mg – 10 in 1 blister pack / 10 in 1 carton NDC 64764-543-30
15 mg – 3 in 1 blister pack / 5 in 1 tray NDC 64764-543-05
30 mg – 10 in 1 blister pack / 10 in 1 carton NDC 64764-544-30
30 mg – 3 in 1 blister pack / 5 in 1 tray NDC 64764-544-05

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.