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Polyethylene Glycol 3350: Uses, Side Effects and Dosage

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Facts
Status:
Prescription (Rx)
Strength:
17 g/17 g
Brand names:
Drug class:
Active ingredient:

Patient information: uses, side effects, how to take - Polyethylene Glycol 3350

How to take

The dose is 17 grams each day or as directed by physician. It should always be taken by mouth. Measure the dose using the dosing cup (or use one heaping tablespoon of powder), stir and dissolve in a glass (4 to 8 oz) of water, juice, soda, coffee, or tea. Taking more than the prescribed dose may cause loss of fluid due to severe diarrhea.

How will it work

Polyethylene Glycol 3350 NF softens the stool and increases the frequency of bowel movements by retaining water in the stool. Your first bowel movement will usually happen in two to four days, although results may vary for individual patients.

How long should I take it

Polyethylene Glycol 3350 NF achieves its best results when used between one and two weeks. You may discontinue taking the drug after you had several satisfactory bowel movements. Should unusual cramps, bloating, or diarrhea occur, consult your physician. Polyethylene Glycol 3350 NF is intended for up to a two week course of therapy. You should not use for a longer time unless directed by your physician.

Next Steps

After successfully completing Polyethylene Glycol 3350 NF therapy (usually between one and two weeks), please discuss with your physician lifestyle changes which may produce more regular bowel habits (adequate dietary and fluid intake, regular exercise).

Who should NOT take Polyethylene Glycol 3350 NF

Polyethylene Glycol 3350 NF should not be used by children. It should not be used by pregnant women unless prescribed by a physician.

Side Effects/Drug Reactions

Occasionally, Polyethylene Glycol 3350 NF may cause nausea, stomach fullness, cramping, diarrhea and/or gas. Do not take if you have symptoms such as nausea, vomiting, abdominal pain or distention, which may be due to bowel obstruction. On rare occasions hives and skin rashes have been reported which are suggestive of an allergic reaction. If you get an allergic reaction you should discontinue the medication and call your physician. If you are allergic to polyethylene glycol, do not use this drug.

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 077706 · View the label on DailyMed

Revision date stated in the text: November 2008

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Drug information for Polyethylene Glycol 3350

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Osmotic Laxative
Active ingredient Polyethylene glycol 3350 17 g/17 g
Dosage form Powder, for solution
Route Oral
Marketing status not in the current FDA NDC Directory
Company (applicant) NEXGEN PHARMA INC
FDA approval ANDA 077706Abbreviated New Drug Application (ANDA) – generic drug Approved September 27, 2006
Manufacturers 1 labelers list this drug on DailyMed
Packages (NDC)
Package
17 g/17 g – 17 g in 1 cup / 72 in 1 case NDC 17856-0457-1
17 g/17 g – 17 g in 1 pouch / 72 in 1 case NDC 17856-0457-2
17 g/17 g – 4 g in 1 pouch / 72 in 1 case NDC 17856-0457-3
17 g/17 g – 4.25 g in 1 pouch / 72 in 1 case NDC 17856-0457-4
17 g/17 g – 8.5 g in 1 cup / 72 in 1 case NDC 17856-0457-5
17 g/17 g – 8.5 g in 1 pouch / 72 in 1 case NDC 17856-0457-6

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.