Nicotrol Nasal (Nicotine): Uses, Side Effects and Dosage

Updated:

June 2024 Facts

Status:

Prescription (Rx)

Strength:

10 mg/mL

Drug class:

Cholinergic Nicotinic Agonist

Active ingredient:

Nicotine

Similar drugs:

Chantix

Patient information: uses, side effects, how to take - Nicotrol Nasal

BEFORE YOU USE — Read information on both sides

BEFORE YOU USE—Read information on both sides

FOLLOW DOSAGE:	WHAT TO EXPECT (First Week):
Use as directed by doctor. But do not use more than 5 times an hour or 40 times in 24 hours. Stop smoking completely during NICOTROL^®NS treatment program.	Hot, peppery feeling in back of throat or nose, sneezing, coughing, watery eyes, or runny nose. To Help Adjust to Spray—use regularly for first week. Side effects will lessen for most people in a few days—don't stop using the Nasal Spray. If side effects do not lessen after a week, call your doctor.

REMOVE CAP:	PRIME PUMP (before first use):
Press in circles on sides of bottle. Pull off cap as shown.	Get a tissue or paper towel. Hold bottle as shown. Press up on bottom with thumb. Pump into tissue until you see a fine spray (6 to 8 times). Throw tissue away.
FOLLOW DIRECTIONS EXACTLY — Questions? (call 1-888-642-6876)

Blow nose if it is not clear. Tilt head back slightly. Hold bottle as shown.	Insert tip of bottle into nostril—as far as is comfortable. Breathe through mouth. Spray once in each nostril. Do not sniff or inhale while spraying. If nose runs, gently sniff to keep the Nasal Spray in nose. Wait 2 or 3 minutes before blowing nose.
	AVOID contact with skin, eyes, and mouth. If bottle breaks, wear rubber gloves, wipe up with paper towel and wash surfaces thoroughly. Do not let nicotine come in contact with your skin, mouth, or eyes. If it does, rinse with plain water immediately. Nicotine overdose can occur when nicotine is absorbed through the skin. If symptoms of overdose occur (see other side for symptoms), call a doctor or Poison Control Center.
Place cap back on bottle after use. Store at room temperature, 59°F to 86°F (15°C to 30°C), out of reach of children. If you don't use the Nasal Spray for 24 hours, prime pump in tissue 1 or 2 times. Most vials of NICOTROL^®NS contain 100 doses (200 sprays), but excessive priming will reduce the amount of medicine available for use. Avoid excessive priming.

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: NDA 020385 · View the label on DailyMed

Revision date stated in the text: June 2024

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Nicotrol Nasal

Rx or OTC

Prescription (Rx)?

This drug is available only with a prescription from a licensed healthcare provider.
Rx

Drug class

Cholinergic Nicotinic Agonist

Active ingredient

Nicotine 10 mg/mL

Dosage form

Spray, metered

Route

Nasal

Marketing status

listed in the FDA NDC Directory

Company (applicant)

PFIZER INC

FDA approval

NDA 020385New Drug Application (NDA) Approved March 22, 1996

Reference listed drug

This is the reference listed drug (RLD) that generics are compared with.

Manufacturers

1 labelers list this drug on DailyMed

Packages (NDC)

Package
10 mg/mL – 10 ml in 1 bottle, spray / 4 in 1 box NDC 0009-5401-01

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.