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Metronidazole Injection (Likmez): Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx) Boxed warning Current since November 3, 2026
Strength:
500 mg/100 mL
Active ingredient:
Similar drugs:

Patient information: uses, side effects, how to take - Metronidazole Injection

Directions for Use

CAUTION: DO NOT ADD SUPPLEMENTARY MEDICATIONS.

For intravenous infusion only

Store the individual container in the aluminum overwrap until ready to use.

Use sterile equipment.

Before use, perform the following checks:

Read the label. Ensure solution is the one ordered and is within the expiration date.

Inspect the solution in good light for cloudiness, haze or particulate matter; check for minute leaks by squeezing the bag firmly. Any container which is suspect should not be used. If leaks are found, discard container as sterility may be compromised.

Use only if solution is clear and the container is undamaged.

Single dose plastic container. Discard unused portion.

Consult Package Insert for complete product information.

Preparation for Administration

  1. 1. Close flow control clamp of administration set.
  2. 2. Caution – adding additives into the Metronidazole Injection solution bag is prohibited. If used with a primary intravenous fluid system, the primary solution should be discontinued during metronidazole infusion. Do not use equipment containing aluminum (e.g., needles, cannulae, etc.) that may contact the drug solution.
  3. 3. Remove cover from port at bottom of container.
  4. 4.

    Insert piercing pin of administration set into port with a twisting motion until the pin is firmly seated.

    NOTE: See full directions on administration set carton.

  5. 5. Suspend container from hanger.
  6. 6. Squeeze and release drip chamber to establish proper fluid level in chamber during infusion of Metronidazole Injection.
  7. 7. Open flow control clamp to expel air from set. Close clamp.
  8. 8. Regulate rate of administration with flow control clamp.

sagent ®

Mfd. for SAGENT Pharmaceuticals

Schaumburg, IL 60173 (USA)

Made in Switzerland

©2026 Sagent Pharmaceuticals

Revised: April 2026

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 206191 · View the label on DailyMed

Revision date stated in the text: April 2026

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Metronidazole Injection

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Boxed warning Yes – this drug has a boxed warning (also called a black box warning), the strongest warning of the FDA.
Drug class Nitroimidazole Antimicrobial
Active ingredient Metronidazole 500 mg/100 mL
Dosage form Injection, solution
Route Intravenous
Marketing status not in the current FDA NDC Directory
Company (applicant) INFORLIFE
FDA approval ANDA 206191Abbreviated New Drug Application (ANDA) – generic drug Approved February 25, 2019
Therapeutic equivalence (TE) code APCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Manufacturers 8 labelers list this drug on DailyMed
Drug shortage
  • Current since November 3, 2026
Packages (NDC)
Package
500 mg/100 mL – 100 ml in 1 bag / 1 in 1 pouch / 24 in 1 carton

Source: FDA drug labeling via NLM DailyMed, data as of November 6, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.