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Lucemyra: Uses, Side Effects and Dosage

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Facts
Status:
Prescription (Rx)
Strength:
0.2 mg
Active ingredient:
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Source: FDA drug labeling via NLM DailyMed · About this document

Patient information: uses, side effects, how to take - Lucemyra

What is the most important information I should know about LUCEMYRA and discontinuing opioid drugs?

LUCEMYRA can cause serious side effects, including low blood pressure (hypotension), slow heart rate (bradycardia), and fainting.

If you have any of the following signs or symptoms, tell your healthcare provider right away:

  • low blood pressure
  • lightheadedness
  • slow heartbeat
  • feeling faint at rest or when standing up
  • dizziness

If you take LUCEMYRA at home and have any of these signs and symptoms, do not take your next dose of LUCEMYRA until you have talked to your healthcare provider. You should avoid becoming dehydrated or overheated during treatment with LUCEMYRA, which may increase your risk of low blood pressure and fainting. You should also be careful not to stand up too suddenly from lying down or sitting.

When your treatment is complete you will need to stop taking LUCEMYRA gradually or your blood pressure could increase. For more information about side effects, see “What are the possible side effects of LUCEMYRA?”

Increased risk of opioid overdose. After a period of time of not using opioids drugs, you can become more sensitive to the effects of opioids if you start using opioids again. This may increase your risk of overdose and death.

What is LUCEMYRA?

LUCEMYRA is a non-opioid prescription medicine used in adults to help with the symptoms of opioid withdrawal that may happen when you stop taking an opioid suddenly.

LUCEMYRA will not completely prevent the symptoms of opioid withdrawal, which may include feeling sick, stomach cramps, muscle spasms or twitching, feeling of cold, heart pounding, muscular tension, aches and pains, yawning, runny eyes and sleep problems (insomnia).

LUCEMYRA is not a treatment for opioid use disorder. If you have been diagnosed with opioid use disorder (opioid addiction), your healthcare provider may prescribe LUCEMYRA as part of a complete treatment program for your opioid use disorder (opioid addiction).

It is not known if LUCEMYRA is safe and effective in children.

Before taking LUCEMYRA, tell your healthcare provider about all of your medical conditions, including if you:

  • have low blood pressure
  • have a slow heart rate
  • have any heart problems, including history of heart attack or a condition called long QT syndrome
  • have liver or kidney problems
  • drink alcohol

  • are pregnant or plan to become pregnant. It is not known if LUCEMYRA can harm your unborn baby.

  • are breastfeeding or plan to breastfeed. It is not known if LUCEMYRA passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with LUCEMYRA.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and any medications you may take for the individual symptoms of opioid withdrawal (such as pain relievers or medications for upset stomach).

Especially tell your healthcare provider if you take benzodiazepines, barbiturates, tranquilizers, or sleeping pills. Taking LUCEMYRA with these medicines can cause serious side effects. Ask your healthcare provider or pharmacist if you are not sure if you are taking any of these medicines.

How should I take LUCEMYRA?

  • Take LUCEMYRA exactly as your healthcare provider tells you to take it.
  • Your healthcare provider may change your dose if needed.
  • Do not change your dose or stop taking LUCEMYRA without talking to your healthcare provider.

  • Take LUCEMYRA with or without food.

  • If you take too much LUCEMYRA, go to the nearest hospital emergency room right away.

What should I avoid while taking LUCEMYRA?

Do not drive, operate heavy machinery, or perform any other dangerous activities until you know how LUCEMYRA affects you.

What are the possible side effects of LUCEMYRA?

The most common side effects of LUCEMYRA include:

  • low blood pressure or symptoms of low blood pressure
  • slow heart rate
  • dizziness such as lightheadednes
  • sleepiness
  • dry mouth

These are not all the possible side effects of LUCEMYRA.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to BioCorRx Pharmaceuticals Inc at 1-833-LUCEMYRA.

How should I store LUCEMYRA?

  • Store LUCEMYRA at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep LUCEMYRA in its original container.
  • Keep LUCEMYRA away from heat and moisture.
  • LUCEMYRA bottles contain desiccant packs to help keep the tablets dry. Do not remove the desiccant packs until all the tablets are used.

Keep LUCEMYRA and all medicines out of the reach of children.

General information about the safe and effective use of LUCEMYRA.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use LUCEMYRA for a condition for which it was not prescribed. Do not give LUCEMYRA to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about LUCEMYRA that is written for health professionals.

What are the ingredients of LUCEMYRA?

Active ingredient: lofexidine.

Inactive ingredients: lactose, citric acid, povidone, microcrystalline cellulose, calcium stearate, sodium lauryl sulphate, and Opadry OY S 9480 (contains indigo carmine and sunset yellow).

Manufactured for:

BioCorRx Pharmaceuticals Inc 2390 E. Orangewood Ave. Suite 570 Anaheim, CA 92806

BioCorRx Pharmaceuticals Inc is the exclusive licensee and distributor of LUCEMYRA in the United States and its territories. ©2026 LUCEMYRA is a registered trademark of BioCorRx Pharmaceuticals Inc.

For more information, go to www.LUCEMYRA.com or call 1-833-LUCEMYRA

This Patient Information has been approved by the U.S. Food and Drug Administration. 000000 Issued: _____

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: NDA 209229 · View the label on DailyMed

Revision date stated in the text: April 2026

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The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Lucemyra

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Active ingredient Lofexidine hydrochloride 0.2 mg
Dosage form Tablet, film coated
Route Oral
Marketing status listed in the FDA NDC Directory
Company (applicant) BIOCORRX PHARMS
FDA approval NDA 209229New Drug Application (NDA) Approved May 16, 2018
Reference listed drug This is the reference listed drug (RLD) that generics are compared with.
Therapeutic equivalence (TE) code ABCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Generics Lofexidine with the same TE code
Manufacturers 2 labelers list this drug on DailyMed
Packages (NDC)
Package
0.2 mg – 36 in 1 bottle NDC 85789-801-36
0.2 mg – 96 in 1 bottle NDC 85789-801-96

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.