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Clonidine Topical 168-Hour: Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx)
Strength:
0.1 mg/24 h, 0.2 mg/24 h, 0.3 mg/24 h
Active ingredient:

Patient information: uses, side effects, how to take - Clonidine Topical 168-Hour

How to Apply the Clonidine Transdermal System

  • Apply the tan, rectangular clonidine transdermal system PATCH once a week, preferably at a convenient time on the same day of the week (i.e., prior to bedtime on Tuesday of week one; prior to bedtime on Tuesday of week two, etc.).

Each carton contains two types of pouches:

Figure 2:

Contains PATCH with medicationContains ADHESIVE COVER for use if the PATCH becomes loose.
  • Select a hairless area such as on the upper, outer arm or upper chest. The area chosen should be free of cuts, abrasions, irritation, scars or calluses and should not be shaved before applying the clonidine transdermal system PATCH. Do not place the clonidine transdermal system PATCH on skin folds or under tight undergarments, since premature loosening may occur.
  • Wash hands with soap and water and thoroughly dry them.
  • Clean the area chosen with soap and water. Rinse and wipe dry with a clean, dry tissue.
  • Select the pouch labeled "Clonidine Transdermal System USP" and open it as illustrated in Figure 3. Remove the tan, rectangular PATCH from the pouch.

Figure 3:

  • Remove the clear adhesive protective backing from the PATCH by gently peeling off one half of the backing at a time as shown in Figure 4. Avoid touching the sticky side of the clonidine transdermal system PATCH.

Figure 4:

  • Place the clonidine transdermal system PATCH on the prepared skin site (sticky side down) by applying firm pressure over the PATCH to ensure good contact with the skin, especially around the edges (Figure 5). Discard the clear adhesive protective backing and wash your hands with soap and water to remove any drug from your hands.

Figure 5:

  • After one week, remove the old PATCH and discard it (refer to Instructions for Disposal). After choosing a different skin site, repeat instructions 2 through 7 for the application of your next clonidine transdermal system PATCH.

What to do if your Clonidine Transdermal System PATCH becomes loose while wearing:

How to Apply the ADHESIVE COVER

Note: The ivory, round, ADHESIVE COVER does not contain any drug and should not be used alone. The COVER should be applied directly over the clonidine transdermal system PATCH only if the PATCH begins to separate from the skin, thereby ensuring that it sticks to the skin for seven full days.

Figure 6:

  • Wash hands with soap and water and thoroughly dry them.
  • Using a clean, dry tissue, make sure that the area around the tan, rectangular clonidine transdermal system PATCH is clean and dry. Press gently on the clonidine transdermal system PATCH to ensure that the edges are in good contact with the skin.
  • Take the ivory, round, ADHESIVE COVER (Figure 6) from the pouch and remove the paper liner backing from the COVER.
  • Carefully center the ivory, round, ADHESIVE COVER over the tan, rectangular clonidine transdermal system PATCH, and apply firm pressure, especially around the edges in contact with the skin.

Instructions for Disposal

KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.

During or even after use, a PATCH contains active medication which may be harmful to infants and children if accidentally applied or ingested. After use, fold in half with the sticky sides together. Dispose of carefully out of reach of children.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Store at 20° to 25°C (68° to 77°F).

Distributed by:

Dr. Reddy’s Laboratories Inc.

Princeton, NJ 08540

Manufactured by:

Corium Innovations, Inc.

Grand Rapids, MI 49512

Rev. 09/2023

CAW1111

About this document

Source: FDA drug labeling via NLM DailyMed · Application number: ANDA 079090 · View the label on DailyMed

Revision date stated in the text: September 2023

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Clonidine Topical 168-Hour

Rx or OTC
Prescription (Rx)?
  • This drug is available only with a prescription from a licensed healthcare provider.
  • Rx
Drug class Central alpha-2 Adrenergic Agonist
Active ingredient Clonidine
Dosage form Patch, extended release
Route Transdermal
Marketing status listed in the FDA NDC Directory
Company (applicant) DR REDDYS LABS SA
FDA approval ANDA 079090Abbreviated New Drug Application (ANDA) – generic drug Approved August 20, 2010
Therapeutic equivalence (TE) code ABCodes starting with A mean the FDA rates the drug therapeutically equivalent to its reference drug (Orange Book).
Generics Catapres-TTS-1 Topical Extended-Release with the same TE code
Manufacturers 2 labelers list this drug on DailyMed
Packages (NDC)
Package
0.1 mg/24 h – 24 h in 1 patch / 1 in 1 pouch / 4 in 1 carton
0.2 mg/24 h – 24 h in 1 patch / 1 in 1 pouch / 4 in 1 carton
0.3 mg/24 h – 24 h in 1 patch / 1 in 1 pouch / 4 in 1 carton

Source: FDA drug labeling via NLM DailyMed, data as of October 31, 2026. FDA data (DailyMed, Orange Book, Drug Shortages, enforcement reports). Not a substitute for the advice of a doctor or pharmacist.